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How Sunlight
Can Save Your Life
 
Diseases Caused By Vitamin D Deficiency
By Oliver Gillie The Independent - UK 1-27-4
Experts hotly debate which diseases may truly be
caused by vitamin D deficiency. Nevertheless the
extent of the evidence and its consistency makes
a powerful case for D-deficiency being an important
cause of over a dozen chronic diseases and almost
as many cancers. Other important factors such as
obesity, lack of exercise, or a diet containing
too many calories, are also known to increase the
risk of many of these diseases. But both obesity
and lack of exercise are linked with D-deficiency
and so the evidence is confused. Vitamin D, is stored
in fat and becomes 'lost' in obese people, while
people who take exercise often spend more time outdoors
in the sun.
Nervous system diseases
Last year Professor John McGrath and others at the
University of Queensland found that pregnant rats
deprived of vitamin D give birth to baby rats with
serious brain abnormalities. This work will eventually
be seen to be as important as the discovery that
folic acid deficiency during pregnancy causes severe
spinal deformities (spina bifida) in offspring,
or that thalidomide given to pregnant animals causes
abnormalities of the limbs. The importance of their
article published in Neuroscience (volume 118, pp641-653)
has not yet been appreciated but it provides a means
of understanding several neurological diseases which
have puzzled doctors for more than a century.
Multiple sclerosis (MS), Schizophrenia, and Parkinson's
disease - people with these diseases are more likely
to have winter or spring birthdays. MS and Parkinson's
diseases are more common in northern countries or
states of America. People with MS have worse symptoms
in winter and brain scans show an increase in damage
to the brain of MS people in winter. Supplements
of vitamin D given to babies may prevent MS and
schizophrenia. A very severe form of Parkinson's
disease occurs in people with dark skin living in
the UK.
Alzheimer's disease and Amyotropic lateral sclerosis
(motor neurone disease) are believed by some neurologists
to be similar in the way they develop to Parkinson's
disease but affecting different parts of the brain
or nervous system. These diseases are several times
more common in black people living in United States
than in black people living in traditional societies
in the Tropics. In northern countries there are
more births of these two diseases in winter.
Autism - people with autism have winter birthdays
more often than would be expected. The cause of
the disease is a mystery, but increased winter birthdays
could be an important clue suggesting that vitamin
D deficiency in pregnancy is a cause, at least in
a proportion of cases.
Autoimmune diseases
These are diseases in which the body is attacked
by its own immune system. Such attacks are generally
thought to be triggered by infection, but deficiency
of vitamin D causing abnormal proliferation of cells
and changes in the immune system may be a key factor.
There are many of these diseases and some are quite
rare. Only a few have been studied in depth.
Diabetes type 1 - a classic autoimmune disease.
It is more common in northern countries and an increase
in winter birthdays have been found in some places.
Vitamin D supplements in pregnancy or first year
of life protects against the disease and vitamin
D may also delay progress of the disease after it
has begun to cause problems.
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